The Regulatory Genome
by Eric H. Davidson · first published 2005
3mentions
2recommended by
2HN commenters
2014–2017first – last mentioned
100% recommend
Explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept.
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The Regulatory Genome: Gene Regulatory Networks In Development And Evolution, by Eric Davidson awesome read.
on “Ask HN: What book are you reading right now?” ↗…eukaryotic gene provides a particular and potentially unique "address" in "Transcription Factor State Space" by which the gene can be controlled. For more information on this amazing topic, check out "The Regulatory Genome" by Eric H. Davidson. Here is an excerpt from the first page of chapter 4: "Whatever their extent, however, development gene regulatory networks have an internal structure, in that they are composed…
on “A programming language for living cells” ↗Also: Istrail S, De-Leon SB, Davidson EH. The regulatory genome and the computer. Dev Biol. 2007 Oct 15;310(2):187-95. Epub 2007 Aug 10. Review. PubMed PMID: 17822690. Full-text: http://www.sciencedirect.com/science/article/pii/S0012160607... Abstract: > "The definitive…
on “Living cells are very fast and crowded places (2012)” ↗