A Crack in Creation
by Jennifer A. Doudna, Samuel H. Sternberg · first published 2017
57% recommend43% neutral
A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manip
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…footnote when it makes the impossible, possible though. We need to keep having these ethics conversations though, so we can use this tool wisely. For further reading I would recommend Jennifer Doudna's "A crack in creation". She is one of the founders of CRISPR as a gene editing tool, and her book is good reading on the topic.
on “We can now edit the human genome – how far should we go? [video]” ↗…causing others? Yes. >Could this type of research lead to a time when humans live two to three times as long? Yes. > Need a fraction of our current food supply? Yes. I suggest anyone interested read A Crack in Creation, by Dr. Jennifer Doudna.
on “First US Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway” ↗…Future for Everyone 4. The Four: The Hidden DNA of Amazon, Apple, Facebook, and Google 5. This Idea Is Brilliant: Lost, Overlooked, and Underappreciated Scientific Concepts Everyone Should Know 6. A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution 7. Easternization: Asia’s Rise and America’s Decline from Obama to Trump and Beyond 8. Astrophysics for People in a Hurry 9. The Woman Who…
on “Best Tech Books of 2017” ↗For anyone interested in learning more, I highly recommend Doudna’s book, “A Crack in Creation” - very readable explanation of the process leading to discovering CRISPR/Cas9. https://www.amazon.co.uk/Crack-Creation-Editing-Unthinkable-...
on “The Nobel Prize in Chemistry 2020” ↗Doudna has her own memoir, "A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution." Why would you read Isaacson's third-person account, when you can get the information from the scientist herself? Well, I read both books,…
on “Books I loved reading this year” ↗>What does Jennifer Doudna think of the probability of catastrophic bioerror? You can find hers (and co-author Sam Sternberg's) opinion on CRISPR as a method to do bioerror in her book "A Crack in Creation".
on “Longbets: A bioerror will lead to one million casualties by Dec 2020” ↗Jennifer Doudna [1] for sure, both for CRISPR and for her stance on the ethical use of it. [2] [1] https://vcresearch.berkeley.edu/faculty/jennifer-doudna [2] https://www.hmhbooks.com/shop/books/A-Crack-in-Creation/9780...
on “Ask HN: What living scientists do you consider heroes?” ↗Thank you for that - I'd recently read A Crack in Creation and thought the same question you had posed.
on “Books I loved reading this year” ↗